Current Treatment for Heart Failure
Most treatment options for heart failure aim to relieve symptoms. Medicines that are effective for treating some types of heart failure often do not work for heart failure with preserved ejection fraction. Currently, there are no commercially available device-based treatment options for these patients.
The IASD® System – A Novel Treatment for Heart Failure
Corvia Medical’s InterAtrial Shunt Device (IASD) is an investigational, non-surgical medical device designed to provide continuous and dynamic decompression of the left atrium, which may reduce symptoms and slow the progression of heart failure.
Placed by an interventional cardiologist during a standard catheter-based procedure, the IASD system creates a very small opening between the left and right atria (the upper chambers of the heart). This opening allows blood to flow from the high pressure left atrium to the low pressure right atrium. This redistribution of blood to the right side potentially reduces the pressure in the left side and in the lungs.
Non-clinical testing demonstrated that the InterAtrial Shunt Device (IASD) is MR Conditional. A patient with this device can be scanned safely in an MR system immediately after placement under the following conditions:
- Static magnetic field of 1.5-Tesla and 3-Tesla, only
- Maximum spatial gradient magnetic field of 4,0000-Gauss/cm (extrapolated) or less
- Maximum MR system reported, whole body averaged specific absorption rate (SAR) of 4-W/kg for 15 minutes of scanning (i.e., per pulse sequence) in the Normal Operating Mode of operation for the MR system
- Under the scan conditions defined, the InterAtrial Shunt Device (IASD) is expected to produce a maximum temperature rise of 1.9°C after 15-minutes of continuous scanning (i.e., per pulse sequence).
In non-clinical testing, the image artifact caused by the InterAtrial Shunt Device (IASD) extends approximately 5-mm from this device when imaged using a gradient echo pulse sequence and a 3-Tesla MR system.